1 MCQs in Medicine for NEET PG
A 58-year-old woman with a remote history of breast cancer presents with a 4-week history of progressive memory loss, confusion, paranoid delusions, and focal seizures with olfactory auras. Brain MRI shows bilateral medial temporal lobe T2/FLAIR hyperintensities. The EEG pattern marked **C** in the diagram (bitemporal slow waves, epileptiform discharges, and frequent focal temporal seizures) is documented. CSF analysis reveals mild lymphocytic pleocytosis and elevated protein. Serum and CSF antibodies are positive for GluA1/GluA2 subunits. Which of the following best explains the mechanism of neuronal dysfunction in this patient?
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