1 MCQs in Medicine for NEET PG
A 52-year-old woman with a 15-year history of asthma presents with persistent dyspnoea, chronic productive cough, and recurrent lower respiratory tract infections. High-resolution CT chest shows bronchial wall thickening with bronchus-to-artery ratio >1 and bronchial dilatation. Spirometry reveals FEV₁/FVC ratio of 0.68 with minimal reversibility after bronchodilators. Which of the following best explains the lack of bronchodilator reversibility in this patient?
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