A 58-year-old male with a 10-year history of chronic GERD on pantoprazole 40 mg daily undergoes surveillance upper GI endoscopy. He is obese (BMI 32), smokes 1 pack per day, and reports nocturnal regurgitation. Endoscopic findings show a salmon-pink tongue of columnar-appearing mucosa extending 3 cm above the gastroesophageal junction (marked **A** in the diagram), in contrast to the surrounding pale pink squamous esophageal mucosa. Systematic four-quadrant biopsies are obtained every 2 cm from this abnormal segment. Which histologic finding on biopsy would confirm the diagnosis of Barrett esophagus?
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