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    SubjectsMedicineBronchial Provocation — Histamine Challenge
    ClinicalMedicine

    Bronchial Provocation — Histamine Challenge

    1 MCQs in Medicine for NEET PG

    1 Hard
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    Sample Questions

    hard

    A 28-year-old woman presents with a 6-month history of intermittent dyspnea and cough, worse at night and with exercise. Baseline spirometry is entirely normal (FEV1 98% predicted, FEV1/FVC 0.82). A histamine bronchial provocation test is performed. The patient develops a 20% fall in FEV1 when exposed to a histamine concentration of 2.5 mg/mL, as marked by **A** in the diagram. Which of the following best describes the clinical significance of this finding?

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