1 MCQs in Medicine for NEET PG
A 58-year-old man with a 15-year history of type 2 diabetes mellitus presents with progressive dyspnea on exertion, orthopnea, and lower limb edema. His BP is 148/92 mmHg, HR 102/min, JVP elevated, and bilateral crackles on lung auscultation. Echocardiography shows LVEF 35%, restrictive mitral inflow pattern, and normal wall thickness. Cardiac catheterization reveals elevated LV end-diastolic pressure (28 mmHg) with normal coronary arteries. Which of the following is the most likely underlying pathophysiological mechanism?
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