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    SubjectsMedicineEosinophilic Granulomatosis with Polyangiitis Churg-Strauss Spirometry
    ClinicalMedicine

    Eosinophilic Granulomatosis with Polyangiitis Churg-Strauss Spirometry

    1 MCQs in Medicine for NEET PG

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    A 48-year-old male with newly diagnosed EGPA (Churg-Strauss syndrome) presents with severe poorly controlled asthma, mononeuritis multiplex, palpable purpura, and eosinophilic myocarditis. Spirometry with flow-volume loops is performed. The pattern marked **A** in the diagram shows reduced FEV1/FVC with a concave expiratory curve and marked bronchodilator reversibility (FEV1 increases from 55% to 72% predicted after albuterol). Which of the following best explains the pathophysiologic mechanism underlying this spirometric finding in EGPA?

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