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    SubjectsMedicineFamilial HCM Pedigree
    ClinicalMedicine

    Familial HCM Pedigree

    1 MCQs in Medicine for NEET PG

    1 Medium
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    Sample Questions

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    A 28-year-old male presents to the cardiology clinic with a family history of sudden cardiac death in his father at age 35. Echocardiography reveals asymmetric septal hypertrophy with a left ventricular wall thickness of 16 mm and a dynamic left ventricular outflow tract (LVOT) gradient. Genetic testing identifies a heterozygous mutation in the MYH7 gene. The inheritance pattern marked **B** in the pedigree diagram is consistent with this finding. Which of the following best describes the inheritance pattern and genetic basis of this patient's condition?

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