1 MCQs in Medicine for NEET PG
A 58-year-old man presents with progressive headache, cognitive decline, and a single seizure. MRI brain shows a ring-enhancing mass crossing the corpus callosum (marked **A**), with central necrosis and extensive perilesional edema. Histopathology confirms a WHO Grade 4 astrocytoma. Which of the following molecular markers is MOST critical for predicting response to temozolomide-based chemotherapy in this patient?
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