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    SubjectsMedicineGPA — ANCA-Associated Vasculitis
    ClinicalMedicine

    GPA — ANCA-Associated Vasculitis

    1 MCQs in Medicine for NEET PG

    1 Medium
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    Sample Questions

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    A 42-year-old woman presents with chronic sinusitis, recurrent epistaxis, hemoptysis, and serum creatinine 2.4 mg/dL. CT chest shows cavitary nodules; urinalysis reveals dysmorphic red cells and red-cell casts. Cytoplasmic ANCA with anti-proteinase-3 (PR3) specificity is strongly positive. A flow-volume loop is obtained as part of her respiratory assessment. The pattern marked **B** in the diagram shows fixed upper-airway obstruction with flattened inspiratory and expiratory loops. Which of the following best explains the anatomical basis of this flow-volume pattern in this patient's condition?

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