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    SubjectsMedicineGranulomatosis with Polyangiitis Spirometry
    ClinicalMedicine

    Granulomatosis with Polyangiitis Spirometry

    1 MCQs in Medicine for NEET PG

    1 Medium
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    A 42-year-old woman with granulomatosis with polyangiitis (GPA) in remission on maintenance rituximab presents with progressive hoarseness, inspiratory stridor, and dyspnea on exertion. Flexible laryngoscopy reveals Grade III subglottic stenosis (6 mm diameter) with inflammatory ulceration and granulation tissue. Pulmonary function testing with flow-volume loops is performed. The pattern marked **A** in the diagram—flattening of both inspiratory and expiratory flow-volume loops with a box-like appearance—is consistent with which of the following pathophysiologic mechanisms?

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