1 MCQs in Medicine for NEET PG
A 42-year-old woman presents with a 3-month history of chronic sinusitis, epistaxis, saddle-nose deformity, hoarseness, and progressive dyspnea on exertion with audible stridor. Laboratory investigations reveal hematuria and c-ANCA positivity with anti-PR3 antibodies. Chest X-ray shows a cavitary lung lesion. Spirometry reveals a fixed upper airway obstruction pattern with flattening of both inspiratory and expiratory limbs of the flow-volume loop (marked as **C** in the diagram), and CT neck confirms circumferential subglottic narrowing. What is the most likely diagnosis?
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