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    SubjectsMedicineHeart Failure—ACE Inhibitor Adverse Effects
    ClinicalMedicine

    Heart Failure—ACE Inhibitor Adverse Effects

    1 MCQs in Medicine for NEET PG

    1 Hard
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    hard

    A 62-year-old woman with a 15-year history of systemic hypertension presents with progressive dyspnea on exertion, orthopnea, and paroxysmal nocturnal dyspnea for 3 months. Her blood pressure is 168/104 mmHg, heart rate 92/min, and physical examination reveals elevated JVP, bilateral ankle edema, and a laterally displaced apex beat. Chest X-ray shows cardiomegaly with bilateral pulmonary edema. Echocardiography reveals an ejection fraction of 35% with global hypokinesis. She is started on lisinopril, metoprolol, and furosemide. After 2 weeks, her symptoms improve, but she develops a dry cough. Which of the following mechanisms best explains the adverse effect she has developed?

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