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    SubjectsMedicineHereditary Sensory and Autonomic Neuropathy (HSAN)
    ClinicalMedicine

    Hereditary Sensory and Autonomic Neuropathy (HSAN)

    1 MCQs in Medicine for NEET PG

    1 Medium
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    A 35-year-old Indian man presents with progressive distal sensory loss, recurrent painless foot ulcers, and neuropathic pain in his lower limbs. Examination reveals insensitivity to pain and temperature in a stocking distribution, preserved motor strength, and normal deep tendon reflexes. His father and paternal grandfather had similar symptoms with adult-onset presentation. The inheritance pattern marked **A** in the diagram is most consistent with this clinical presentation. Which of the following genetic subtypes and inheritance patterns best explains this pedigree?

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