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    SubjectsMedicineLimb-Girdle Muscular Dystrophy Type 2A / R1 (Calpainopathy / CAPN3) - Autosomal Recessive Pedigree
    ClinicalMedicine

    Limb-Girdle Muscular Dystrophy Type 2A / R1 (Calpainopathy / CAPN3) - Autosomal Recessive Pedigree

    1 MCQs in Medicine for NEET PG

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    A 19-year-old woman from Kerala presents with a 5-year history of progressive proximal weakness, waddling gait, and difficulty rising from a chair using a modified Gowers' maneuver. She has selective atrophy of hamstrings, gluteal, and scapular stabilizer muscles with scapular winging. Serum CK is 4200 U/L. Her parents are first cousins; two of her six siblings have identical symptoms, while three are entirely unaffected. All parents and grandparents are asymptomatic with normal strength. The pedigree pattern marked **C** in the diagram shows which inheritance pattern?

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