1 MCQs in Medicine for NEET PG
A 62-year-old man presents with bone pain and fatigue. Serum protein electrophoresis shows an M-spike, and bone marrow biopsy reveals 45% plasma cells. FISH cytogenetics shows the pattern marked **B** in the diagram — multiple gains with trisomies of chromosomes 3, 5, 7, 9, 11, 15, 19, and 21. Total chromosome count is 52. According to current risk stratification (mSMART/R-ISS), this cytogenetic finding places the patient in which risk category?
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