1 MCQs in Medicine for NEET PG
A 52-year-old man with BMI 38 kg/m² presents with morning headaches, daytime somnolence, and witnessed apneas. Arterial blood gas shows pH 7.37, PaCO2 52 mmHg, HCO3 32 mEq/L on room air while awake. Spirometry reveals FVC 65% predicted, FEV1 68% predicted, FEV1/FVC ratio 0.78, and TLC 70% predicted. The spirometric pattern marked **B** in the diagram is consistent with obesity hypoventilation syndrome. Which of the following is the most appropriate first-line management for this patient?
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