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    SubjectsMedicineRestrictive Spirometry in Ankylosing Spondylitis
    ClinicalMedicine

    Restrictive Spirometry in Ankylosing Spondylitis

    1 MCQs in Medicine for NEET PG

    1 Medium
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    A 42-year-old HLA-B27-positive man with a 20-year history of ankylosing spondylitis and complete thoracolumbar spine fusion presents with progressive exertional dyspnea. Spirometry shows FVC 2.85 L (68% predicted) and FEV1 2.40 L (72% predicted) with FEV1/FVC ratio 0.84. Body plethysmography confirms total lung capacity of 4.4 L (67% predicted). The parameter marked **C** in the spirometric interpretation—preserved DLCO/VA (KCO) at 115% predicted—indicates which of the following about the origin of his restrictive physiology?

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