1 MCQs in Medicine for NEET PG
A 55-year-old man with a 15-year history of pulmonary sarcoidosis presents with progressive dyspnea at rest, productive cough, and hemoptysis. Examination reveals clubbing, cyanosis (SpO₂ 88% on room air), and bilateral coarse crackles at the upper lung zones. Chest X-ray shows extensive bilateral upper-zone reticulonodular opacities with honeycombing and a right apical cavity with an air-crescent sign (aspergillus mycetoma). HRCT confirms upper-lobe predominant fibrosis with traction bronchiectasis and architectural distortion. The spirometry pattern marked **C** in the diagram is obtained. Which of the following BEST explains the physiological basis for the reduced FEV₁/FVC ratio (0.62) observed in this patient's spirometry?
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