1 MCQs in Medicine for NEET PG
A 52-year-old woman with systemic sclerosis presents with progressive dyspnea on exertion for 3 months. Chest X-ray is normal. Spirometry shows FEV₁ 88% predicted, FVC 90% predicted, FEV₁/FVC ratio 0.82. TLC is 95% predicted. However, DLCO is 55% predicted with DLCO/VA (KCO) also reduced. The spirometry and lung volumes pattern shown in the diagram corresponds to the finding marked **A** — isolated DLCO reduction with normal spirometry. Which of the following is the most likely mechanism underlying this pattern in this patient?
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