1 MCQs in Medicine for NEET PG
A 52-year-old male with chronic alcohol use disorder presents with confusion, horizontal nystagmus with bilateral lateral rectus palsies, and broad-based gait ataxia. MRI FLAIR shows symmetric hyperintensity in the medial thalami and mammillary bodies with post-contrast enhancement. Serum thiamine is severely depleted. The EEG pattern marked **B** in the diagram—generalized theta-delta slowing with frontal intermittent rhythmic delta activity (FIRDA)—reflects the underlying metabolic derangement in this patient. Which of the following best explains the neurophysiological basis for this EEG pattern in acute Wernicke encephalopathy?
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