3 MCQs in Microbiology for NEET PG
Which of the following viral proteins is responsible for the proteolytic cleavage of the poliovirus polyprotein into functional viral proteins?
A 3-year-old boy from rural Maharashtra presents with acute onset flaccid paralysis of the lower limbs over 48 hours. His mother reports he was unvaccinated due to religious beliefs. On examination, he has symmetric weakness of bilateral lower extremities with hyporeflexia and normal sensation. Cerebrospinal fluid analysis shows lymphocytic pleocytosis with normal glucose and protein. Stool culture grows poliovirus type 1. What is the most likely pathophysiological mechanism underlying his paralysis?
Poliovirus is a non-enveloped RNA virus belonging to which genus of the Picornaviridae family?
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