Salmonella — Enteric Fever

Which of the following flagellar antigens is most commonly associated with Salmonella typhi and is used in the Widal test for diagnosis of enteric fever?

A 28-year-old man from rural Uttar Pradesh presents with a 10-day history of sustained fever (39.5°C), headache, and abdominal discomfort. He reports rose spots on the trunk, splenomegaly on examination, and a relative bradycardia (pulse 78/min despite fever). Blood culture obtained on day 3 of illness grows a Gram-negative rod that is oxidase-negative, ferments glucose and mannitol, produces H₂S, and is motile. The organism is negative for lactose fermentation and VP test. What is the most likely diagnosis?

A 28-year-old man from Delhi presents with a 2-week history of sustained fever, headache, and abdominal distension. Blood culture yields a gram-negative rod. Which Salmonella species is the most common cause of enteric fever in India?

A 28-year-old man from Delhi presents with a 10-day history of sustained fever (39.5°C), headache, myalgia, and rose spots on the trunk. Blood culture is positive for Salmonella typhi. He is currently on ceftriaxone 2 g IV 12-hourly. On day 3 of therapy, his fever persists, and he develops altered mental status with neck stiffness. What is the most appropriate next step in management?

A 28-year-old man from Delhi presents with a 10-day history of sustained fever, headache, rose spots on the trunk, and hepatosplenomegaly. Blood culture grows Salmonella typhi. He has no contraindications to any antibiotic. What is the drug of choice for uncomplicated enteric fever in this patient?