A 24-year-old primigravida at 14 weeks of gestation undergoes routine obstetric ultrasound. The structure marked **A** in the diagram shows absent cranial vault above the orbits with exposed brain tissue floating in amniotic fluid. The patient reports irregular dietary intake and denies folic acid supplementation before conception. Which of the following is the most important modifiable risk factor that likely contributed to this neural tube defect?
A 28-year-old primigravida at 16 weeks gestation presents for routine antenatal screening. Maternal serum alpha-fetoprotein (MSAFP) is markedly elevated at 8 MoM. Ultrasound confirms the diagnosis shown in the diagram as structure **B**. The patient is counseled that this condition is incompatible with life. Which of the following is the PRIMARY PATHOPHYSIOLOGICAL BASIS for the lethal nature of this defect?
Ready to test yourself?
Test your OBG knowledge with AI-powered MCQs and detailed explanations — no signup required to try.
Sign up free and practice all 2 Anencephaly MCQs with AI-powered explanations tailored to your performance.
Create Free Account