Cervical Cancer Staging and Management

A 38-year-old woman is diagnosed with stage IB1 cervical cancer (tumor size 2.5 cm, no parametrial involvement) on biopsy. Before treatment planning, which investigation is most appropriate for staging and assessing distant metastases?

A 52-year-old postmenopausal woman from Rajasthan presents with vaginal bleeding for 3 months. Cervical examination reveals a friable, bleeding mass. Biopsy confirms squamous cell carcinoma of the cervix. Staging investigations (MRI pelvis and CT chest) show a 4 cm cervical lesion with parametrial invasion but no distant metastases. The tumor does not involve the pelvic sidewall or bladder/rectum. According to FIGO 2009 staging, what is the most likely stage of this malignancy?

A 48-year-old woman with a 15-pack-year smoking history presents with persistent vaginal bleeding and a visible cervical lesion on speculum examination. Cervical biopsy confirms squamous cell carcinoma, stage IB1 (tumour size 2.5 cm, no parametrial involvement). She undergoes radical hysterectomy with pelvic lymphadenectomy. Histopathology reveals tumour invading the outer third of the cervical stroma with 2 out of 15 pelvic lymph nodes involved. According to current FIGO 2009 staging, what is the most appropriate stage for this patient?

A 42-year-old woman with stage IB2 cervical cancer (squamous cell carcinoma) is being counseled about treatment options. Regarding the management of stage IB2 cervical cancer, all of the following are standard-of-care approaches EXCEPT:

A 42-year-old woman with newly diagnosed stage IB cervical cancer (squamous cell carcinoma, 4 cm lesion) is counseled regarding treatment options. She has no distant metastases and normal renal function. What is the drug of choice for concurrent chemoradiation therapy in this patient?