An Rh-negative woman at 32 weeks gestation with a positive indirect Coombs test and evidence of Rh sensitization presents with signs of fetal hemolytic disease. Intrauterine transfusion is planned. Which agent is the drug of choice to reduce hemolysis and improve fetal survival in this scenario?
A 28-year-old primigravida with Rh-negative blood group presents at 28 weeks of gestation for routine antenatal care. Indirect Coombs test is negative and there is no clinical evidence of sensitization. What is the drug of choice for prevention of Rh isoimmunisation at this gestation?
A 28-year-old primigravida at 34 weeks of gestation presents with a history of transfusion with unmatched blood during a motor vehicle accident 10 years ago. She is Rh-negative and her partner is Rh-positive. Antenatal screening shows an indirect Coombs test (ICT) positive at 1:16 dilution. Which investigation is most appropriate to assess the severity of fetal hemolytic disease and guide management?
An Rh-negative unsensitised woman delivers an Rh-positive baby. Kleihauer–Betke test shows a fetomaternal haemorrhage of 2 mL of fetal red blood cells. What is the most common reason for failure to prevent Rh isoimmunisation in this scenario?
A 32-year-old Rh-negative primigravida at 34 weeks gestation presents with vaginal bleeding (500 mL). She is unsensitised (negative indirect Coombs test). Regarding management of Rh isoimmunisation risk in this case, all of the following are appropriate EXCEPT:
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