1 MCQs in Ophthalmology for NEET PG
A 78-year-old male presents with sudden onset metamorphopsia and dense central scotoma in the left eye over four days. AMSLER grid shows central scotoma with adjacent wavy lines. Dilated funduscopy reveals a greyish-green subretinal lesion at the fovea surrounded by fresh subretinal hemorrhage, hard lipid exudates, and serous neurosensory detachment. Fluorescein angiography shows early lacy hyperfluorescence with late leakage, and OCT confirms intraretinal and subretinal fluid with hyperreflective pigment epithelial detachment. The structure marked **B** in the diagram represents the greyish subretinal choroidal neovascular membrane. Which of the following is the PRIMARY MECHANISM by which anti-VEGF agents (ranibizumab, aflibercept, brolucizumab) halt progression of this lesion?
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