1 MCQs in Ophthalmology for NEET PG
A 52-year-old woman with systemic lupus erythematosus has been on hydroxychloroquine 400 mg daily (6.2 mg/kg real body weight) for 8 years. She is asymptomatic but routine screening ophthalmology reveals the fundoscopic appearance marked **B** in the diagram—a parafoveal ring of retinal pigment epithelium depigmentation with central foveal sparing. Which of the following best describes the pathophysiologic mechanism underlying this retinal toxicity pattern?
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