Lens Dislocation

A 28-year-old man presents with sudden-onset blurred vision and floaters in the right eye following a blunt trauma to the face during a cricket match. On examination, visual acuity is 6/36 in the right eye. Slit-lamp examination reveals a tremulous iris (iridodonesis) and a white reflex defect superiorly. Gonioscopy shows the lens zonules are intact inferiorly but absent superiorly. What is the most likely diagnosis?

A 35-year-old woman with a known history of Marfan syndrome presents with acute onset of floaters and flashing lights in her left eye. On examination, visual acuity is 6/9 in the affected eye. Slit-lamp examination reveals an inferiorly dislocated lens with the superior edge of the lens visible in the pupil. Fundoscopy shows no retinal detachment. Intraocular pressure is 24 mmHg. What is the most appropriate immediate management?

A 42-year-old woman with a 10-year history of homocystinuria presents to the ophthalmology clinic with gradual vision loss in both eyes over 6 months. On slit-lamp examination, she has bilateral lens opacities with the lens edges visible at the pupillary border, and the zonules appear fragmented and broken. She also has a history of deep vein thrombosis 2 years ago. What is the most appropriate immediate management for her lens dislocation?

In Marfan syndrome, lens dislocation occurs due to defective fibrillin-1. Which direction is the lens typically displaced?

A 28-year-old man presents to the ophthalmology clinic with progressive blurring of vision in both eyes over the past 6 months. He reports a history of recurrent joint dislocations and reports that his father had similar eye problems. On examination, visual acuity is 6/36 in both eyes. Slit-lamp examination reveals bilateral superior lens dislocation with the lens edge visible in the pupil. Gonioscopy shows angle-closure configuration. What is the most likely underlying diagnosis?