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    SubjectsPathologyAnaplastic Large Cell Lymphoma t(2;5)
    Para-clinicalPathology

    Anaplastic Large Cell Lymphoma t(2;5)

    1 MCQs in Pathology for NEET PG

    1 Medium
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    Sample Questions

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    A 22-year-old male presents with fever, weight loss, and cervical lymphadenopathy for 3 weeks. Lymph node biopsy shows large pleomorphic cells with horseshoe-shaped nuclei, strong CD30 positivity, and both cytoplasmic and nuclear ALK immunostaining. Interphase FISH confirms the translocation marked **B** in the diagram. Which of the following best describes the molecular consequence of this translocation?

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