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    SubjectsPathologyBronchiectasis in Cystic Fibrosis
    Para-clinicalPathology

    Bronchiectasis in Cystic Fibrosis

    1 MCQs in Pathology for NEET PG

    1 Medium
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    Sample Questions

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    A 19-year-old female with cystic fibrosis (homozygous ΔF508 CFTR mutation, confirmed by elevated sweat chloride >90 mmol/L) presents with chronic productive cough, hemoptysis, and progressive dyspnea. High-resolution CT chest shows signet-ring sign and tram-track lines with upper lobe predominance. Macroscopic examination of the resected lobe reveals the structure marked **A** — cystic dilatation of subsegmental bronchi with thickened walls. Microscopically, this structure demonstrates loss of ciliated epithelium, squamous metaplasia, and disorganization of smooth muscle and elastin. Which of the following best describes the pathological classification of the bronchiectasis shown in structure **A**?

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