40 MCQs in Pathology for NEET PG
Which chromosomal abnormality is the hallmark of chronic myeloid leukemia and results from a reciprocal translocation between chromosomes 9 and 22?
Which cytogenetic abnormality in chronic lymphocytic leukemia is associated with the most favorable prognosis and is detected by fluorescence in situ hybridization (FISH)?
In chronic lymphocytic leukemia, which immunophenotypic marker combination is most characteristic: CD5+, CD19+, CD23+, and surface immunoglobulin expression?
A 55-year-old man is diagnosed with chronic myelomonocytic leukemia (CMML) with 8% blasts in bone marrow and monosomy 7 cytogenetics. He is transfusion-dependent and symptomatic. Which agent is the preferred first-line treatment?
A 72-year-old man from Mumbai presents with progressive fatigue and lymphadenopathy. Complete blood count shows WBC 15,000/μL with 70% lymphocytes. Bone marrow biopsy reveals lymphocytic infiltration. Flow cytometry shows CD5+, CD19+, CD23+ B cells. What is the most common chronic leukemia in this age group?
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