1 MCQs in Pathology for NEET PG
A 58-year-old man with a 40-pack-year smoking history and COPD (FEV₁ 35% predicted) presents with progressive dyspnea, orthopnea, and ankle edema over 6 months. Examination reveals JVD with prominent A waves, a parasternal heave, loud P2, and a pulsatile hepatomegaly. Chest X-ray shows an enlarged main pulmonary artery. The structure marked **C** in the diagram (dilated main pulmonary artery) is a consequence of chronic pulmonary hypertension secondary to his lung disease. Which of the following mechanisms BEST explains the pathophysiology of cor pulmonale in this patient?
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