1 MCQs in Pathology for NEET PG
A 52-year-old man with type 2 diabetes mellitus of 15 years' duration presents with nephrotic-range proteinuria (4.2 g/day) and eGFR of 38 mL/min/1.73m². Kidney biopsy is performed. Light microscopy shows PAS-positive, eosinophilic, acellular rounded nodules in the glomerular mesangium with compression of surrounding capillary loops. The structure marked **A** in the diagram represents these characteristic lesions. Which of the following best describes the pathogenetic mechanism underlying the formation of this structure?
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