2 MCQs in Pathology for NEET PG
A 58-year-old man presents with a 3-week history of progressive headache, morning vomiting, and recent-onset focal seizures. MRI brain shows a large heterogeneous mass in the right frontal lobe with central necrosis, ring enhancement, and significant peritumoral edema. Histopathology reveals the structure marked **A** — tumor cells arranged in a palisading pattern surrounding a central area of necrosis. Which of the following best explains the pathobiological significance of this finding in establishing the diagnosis and prognosis?
A 68-year-old man presents with a 6-week history of progressive morning headaches and recent-onset focal seizures. MRI brain with contrast reveals a heterogeneous mass in the left frontal lobe with central necrosis and ring enhancement. Histopathology shows densely packed tumor cells arranged in a characteristic "palisade" pattern around the central necrotic area, as marked by **B** in the diagram. Which of the following best describes the pathological significance of this finding marked **B**?
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