1 MCQs in Pathology for NEET PG
A 42-year-old woman presents with progressive fatigue, weight gain, cold intolerance, and delayed relaxation of her Achilles reflex. On examination, she has a firm, rubbery goiter and non-pitting edema of the face and hands. Thyroid biopsy shows dense lymphocytic infiltrate with germinal centers, atrophic follicles, and the structure marked **B** — large eosinophilic granular cells packed with mitochondria. Which of the following best describes the pathophysiologic basis of her primary hypothyroidism?
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