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    SubjectsPathologyHepatocellular Carcinoma - Trabecular Pseudoglandular Pattern with Mallory-Denk Bodies
    Para-clinicalPathology

    Hepatocellular Carcinoma - Trabecular Pseudoglandular Pattern with Mallory-Denk Bodies

    1 MCQs in Pathology for NEET PG

    1 Medium
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    Sample Questions

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    A 58-year-old man with a 20-year history of hepatitis B cirrhosis presents for routine surveillance imaging. A contrast-enhanced CT abdomen reveals a 2.5 cm nodule in the right lobe showing arterial phase hyperenhancement with delayed venous phase washout. Histopathology of the nodule shows tumor cells arranged in **thick trabeculae** (marked **A** in the diagram) that are greater than 3 cells wide, with polygonal eosinophilic hepatocytes and prominent nucleoli. Which of the following best explains why the presence of **thick trabeculae** is a key diagnostic feature of this lesion?

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