A 52-year-old never-smoking woman undergoes routine chest CT for dyspnea and is found to have a peripheral spiculated mass with pleural retraction in the right lower lobe, as marked **B** in the diagram. Tissue diagnosis confirms lung adenocarcinoma. Molecular profiling reveals an EGFR exon 19 deletion. Which of the following is the most appropriate first-line targeted therapy for this patient's advanced disease?
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