A 35-year-old man from rural Uttar Pradesh presents with a 6-week history of fever, agitation, and hydrophobia following a dog bite to his hand. He deteriorates rapidly and dies despite supportive care. Postmortem brain biopsy is performed. The structure marked **A** in the diagram is identified within pyramidal neurons of the hippocampus. What is the diagnostic significance of this finding?
A 35-year-old farmer from rural Uttar Pradesh presents with a 2-week history of fever, agitation, and hydrophobia following a dog bite 6 weeks ago. He did not receive post-exposure prophylaxis. Brain biopsy shows eosinophilic cytoplasmic inclusions within neurons. The structure marked **D** in the diagram is noted on histopathology. Which of the following statements about this finding is most accurate?
Ready to test yourself?
Test your Pathology knowledge with AI-powered MCQs and detailed explanations — no signup required to try.
Sign up free and practice all 2 Negri Bodies — Rabies MCQs with AI-powered explanations tailored to your performance.
Create Free Account