1 MCQs in Pathology for NEET PG
A 30-year-old G2P1 woman at 28 weeks gestation with blood group AB positive presents with decreased fetal movements and polyhydramnios. Antibody screen is negative. Ultrasound shows marked fetal skin edema >5 mm over scalp and abdomen, bilateral pleural effusions, massive ascites, pericardial effusion, and a thickened hydropic placenta. MCA-PSV is 1.9 MoM. Cordocentesis reveals fetal hemoglobin 3.8 g/dL, parvovirus B19 IgM positive, and high-titer parvovirus B19 DNA. The structure marked **A** in the diagram (generalized subcutaneous skin edema with puffy appearance) is a hallmark finding of non-immune hydrops. Which of the following is the MOST LIKELY underlying mechanism responsible for the development of anasarca in this case?
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