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    SubjectsPathologyPlasma Cells in Multiple Myeloma
    Para-clinicalPathology

    Plasma Cells in Multiple Myeloma

    1 MCQs in Pathology for NEET PG

    1 Medium
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    Sample Questions

    medium

    A 65-year-old man presents with bone pain and fatigue. Bone marrow biopsy shows 35% clonal plasma cells. Morphology reveals cells with an eccentric nucleus pushed to one side, prominent perinuclear pale cytoplasm, and basophilic cytoplasm. The structure marked **A** in the diagram represents an atypical plasma cell with these features. Which of the following best explains the functional significance of the perinuclear pale region (hof) in these neoplastic plasma cells?

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