Pyoderma Gangrenosum — IBD-Associated Ulcer

A 32-year-old woman with a 5-year history of ulcerative colitis presents with a rapidly expanding, exquisitely painful ulcer on her left shin with violaceous undermined edges and a necrotic base. The lesion began as a small pustule 2 weeks ago. Her gastroenterologist suspects pyoderma gangrenosum (PG) and refers her to dermatology. The feature marked **D** in the diagram — pathergy, or worsening with trauma — is a hallmark of PG and has critical implications for management. Which of the following management decisions is MOST appropriate given the presence of pathergy in this patient?