Vasculitis Syndromes

A 35-year-old woman with a history of recurrent oral and genital ulcers, ocular inflammation, and arthritis presents with acute chest pain and dyspnea. Chest X-ray shows a widened mediastinum. Which investigation is most appropriate to confirm the diagnosis of Behçet disease with vascular involvement?

A 58-year-old man presents with constitutional symptoms, palpable purpura on lower extremities, and glomerulonephritis. Serum complement levels are normal. Which of the following is NOT a characteristic feature of polyarteritis nodosa (PAN)?

A 52-year-old Indian man presents with sudden-onset chest pain, acute myocardial infarction on ECG, and coronary angiography shows no atherosclerotic disease. Histology of the coronary artery reveals granulomatous inflammation with giant cells and medial necrosis. Which vasculitis syndrome best explains this presentation?

A 72-year-old woman with a 3-month history of headache, jaw claudication, and visual symptoms is found to have elevated ESR (95 mm/h) and temporal artery biopsy showing granulomatous inflammation with giant cells. Which of the following is NOT true regarding giant cell (temporal) arteritis (GCA)?

A 58-year-old man from Delhi presents with a 3-week history of fever, malaise, and progressive headache. Examination reveals temporal artery tenderness and jaw claudication. ESR is 92 mm/h and CRP is elevated. Temporal artery ultrasound shows a halo sign. What is the most appropriate next step in management?